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On-demand radiosynthesis of N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB) on an electrowetting-on-dielectric microfluidic chip for (18)F-labeling of protein

An all-electronic, droplet-based batch microfluidic device, operated using the electrowetting on dielectric (EWOD) mechanism was developed for on-demand synthesis of N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB), the most commonly used (18)F-prosthetic group for biomolecule labeling. In order...

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Detalles Bibliográficos
Autores principales: Kim, Hee-Kwon, Javed, Muhammad Rashed, Chen, Supin, Zettlitz, Kirstin A., Collins, Jeffrey, Wu, Anna M., Kim, Chang-Jin “C. J.”, Michael van Dam, R., Keng, Pei Yuin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072849/
https://www.ncbi.nlm.nih.gov/pubmed/35530758
http://dx.doi.org/10.1039/c9ra06158d