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Highly stereoselective gram scale synthesis of all the four diastereoisomers of Boc-protected 4-methylproline carboxylates

A general and practical synthetic process for all the four diastereoisomers of Boc-protected 4-methylproline carboxylates has been developed with essentially complete stereoselectivity on the gram scale, which represents the most diastereoselective preparation of 4-methylproline derivatives to date....

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Detalles Bibliográficos
Autores principales: Sun, Kehuan, Tao, Cheng, Long, Bohua, Zeng, Xiaobin, Wu, Zhengzhi, Zhang, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072942/
https://www.ncbi.nlm.nih.gov/pubmed/35530808
http://dx.doi.org/10.1039/c9ra06827a