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Inhibition of Porphyromonas gingivalis peptidyl arginine deiminase, a virulence factor, by antioxidant-rich Cratoxylum cochinchinense: In vitro and in silico evaluation

Porphyromonas gingivalis, the cause of periodontitis, is also linked to many systemic disorders due to its citrullination capability from a unique peptidyl arginine deiminase (PPAD). Protein citrullination is able to trigger an autoimmune response, increasing the severity of rheumatoid arthritis. Th...

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Detalles Bibliográficos
Autores principales: Tan, Sheri-Ann, Yam, Hok Chai, Cheong, Siew Lee, Chow, Yoke Chan, Bok, Chui Yin, Ho, Jia Min, Lee, Pei Yin, Gunasekaran, Baskaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073004/
https://www.ncbi.nlm.nih.gov/pubmed/35531186
http://dx.doi.org/10.1016/j.sjbs.2021.12.037