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Inhibition of Porphyromonas gingivalis peptidyl arginine deiminase, a virulence factor, by antioxidant-rich Cratoxylum cochinchinense: In vitro and in silico evaluation
Porphyromonas gingivalis, the cause of periodontitis, is also linked to many systemic disorders due to its citrullination capability from a unique peptidyl arginine deiminase (PPAD). Protein citrullination is able to trigger an autoimmune response, increasing the severity of rheumatoid arthritis. Th...
Autores principales: | Tan, Sheri-Ann, Yam, Hok Chai, Cheong, Siew Lee, Chow, Yoke Chan, Bok, Chui Yin, Ho, Jia Min, Lee, Pei Yin, Gunasekaran, Baskaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073004/ https://www.ncbi.nlm.nih.gov/pubmed/35531186 http://dx.doi.org/10.1016/j.sjbs.2021.12.037 |
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