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Study on the intestinal permeability of lamivudine using Caco-2 cells monolayer and Single-pass intestinal perfusion

BACKGROUND: The aim of this work is to investigate the intestinal permeability of lamivudine and explore its absorption mechanism. METHOD: Caco-2 cells monolayer and single-pass intestinal perfusion (SPIP) were selected for the investigation of lamivudine under different conditions, such as differen...

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Detalles Bibliográficos
Autores principales: Huang, Weiyin, Chen, Shuang, Sun, Lin, Wwang, Hubin, Qiao, Hongqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073044/
https://www.ncbi.nlm.nih.gov/pubmed/35531213
http://dx.doi.org/10.1016/j.sjbs.2021.11.052