Global characterization of modifications to the charge isomers of IgG antibody

Posttranslational modifications of antibody products affect their stability, charge distribution, and drug activity and are thus a critical quality attribute. The comprehensive mapping of antibody modifications and different charge isomers (CIs) is of utmost importance, but is challenging. We intend...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Xinling, Mi, Wei, Hu, Zhishang, Li, Xiaoyu, Meng, Bo, Zhao, Xinyuan, Qian, Xiaohong, Zhu, Tao, Ying, Wantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073142/
https://www.ncbi.nlm.nih.gov/pubmed/35573890
http://dx.doi.org/10.1016/j.jpha.2020.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073142/
https://www.ncbi.nlm.nih.gov/pubmed/35573890
http://dx.doi.org/10.1016/j.jpha.2020.11.006

Ejemplares similares