Regulation of drug release performance using mixed doxorubicin-doxorubicin dimer nanoparticles as a pH-triggered drug self-delivery system

A mixed drug self-delivery system (DSDS) with high drug content (>50%) was developed to regulate pH-triggered drug release, based on two doxorubicin (DOX)-DOX dimmers: D-DOX(ADH) and D-DOX(car) conjugated with acid-labile dynamic covalent bonds (hydrazone and carbamate, respectively) and stabiliz...

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Detalles Bibliográficos
Autores principales: Li, Jiagen, Li, Xinming, Xie, Pengwei, Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073254/
https://www.ncbi.nlm.nih.gov/pubmed/35573875
http://dx.doi.org/10.1016/j.jpha.2021.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073254/
https://www.ncbi.nlm.nih.gov/pubmed/35573875
http://dx.doi.org/10.1016/j.jpha.2021.03.001

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