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Regulation of drug release performance using mixed doxorubicin-doxorubicin dimer nanoparticles as a pH-triggered drug self-delivery system
A mixed drug self-delivery system (DSDS) with high drug content (>50%) was developed to regulate pH-triggered drug release, based on two doxorubicin (DOX)-DOX dimmers: D-DOX(ADH) and D-DOX(car) conjugated with acid-labile dynamic covalent bonds (hydrazone and carbamate, respectively) and stabiliz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073254/ https://www.ncbi.nlm.nih.gov/pubmed/35573875 http://dx.doi.org/10.1016/j.jpha.2021.03.001 |