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Enhanced extracellular recombinant keratinase activity in Bacillus subtilis SCK6 through signal peptide optimization and site-directed mutagenesis

Keratinase has a great commercial value owing to its applications in the enzymatic dehairing of goatskins. In this study, we adopted a combined strategy to enhance the extracellular recombinant keratinase activity in Bacillus subtilis SCK6. First, nine signal peptides were screened to enhance the ex...

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Detalles Bibliográficos
Autores principales: Tian, Jiewei, Long, Xiufeng, Tian, Yongqiang, Shi, Bi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073338/
https://www.ncbi.nlm.nih.gov/pubmed/35529123
http://dx.doi.org/10.1039/c9ra07866e