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ZnBr(2)/Oxone-mediated ipso-cyclization of N-(3-phenylprop-2-yn-1-yl)aniline
In this work, a selective synthetic strategy towards 1-azaspiro[4.5]deca-3,6,9-trien-8-ones from N-tosyl-N-(prop-2-yn-1-yl)aniline is developed. The transformation proceeds smoothly in a mixed solvent including acetonitrile and water when ZnBr(2) and Oxone are employed. Mechanism studies show that t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073544/ https://www.ncbi.nlm.nih.gov/pubmed/35529126 http://dx.doi.org/10.1039/c9ra06646b |