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Intratumoral expression analysis reveals that OX40 and TIM-3 are prominently expressed and have variable associations with clinical outcomes in high grade serous ovarian cancer

Patients with ovarian cancer exhibit low response rates to anti-programmed cell death protein-1 (PD-1) based therapies, despite ovarian tumors demonstrating measurable immune responses. Therefore, the aim of the present study was to comparatively examine expression of notable immune co-stimulatory a...

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Detalles Bibliográficos
Autores principales: James, Nicole E., Valenzuela, Ashley D., Emerson, Jenna B., Woodman, Morgan, Miller, Katherine, Hovanesian, Virginia, Ou, Joyce, Ribeiro, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073576/
https://www.ncbi.nlm.nih.gov/pubmed/35527785
http://dx.doi.org/10.3892/ol.2022.13308