Genome maintenance in retinoblastoma: Implications for therapeutic vulnerabilities

Retinoblastoma (RB) is a pediatric ocular malignancy that is initiated mostly by biallelic inactivation of the RB transcriptional corepressor 1 (RB1) tumor suppressor gene in the developing retina. Unlike the prevailing prediction based on multiple studies involving RB1 gene disruption in experiment...

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Detalles Bibliográficos
Autores principales: Lee, Chunsik, Kim, Jong Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073582/
https://www.ncbi.nlm.nih.gov/pubmed/35527780
http://dx.doi.org/10.3892/ol.2022.13312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073582/
https://www.ncbi.nlm.nih.gov/pubmed/35527780
http://dx.doi.org/10.3892/ol.2022.13312

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