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Perphenazine and prochlorperazine decrease glioblastoma U-87 MG cell migration and invasion: Analysis of the ABCB1 and ABCG2 transporters, E-cadherin, α-tubulin and integrins (α3, α5, and β1) levels

Glioblastoma multiforme is the most frequent type of malignant brain tumor, and is one of the most lethal and untreatable human tumors with a very poor survival rate. Therefore, novel and effective strategies of treatment are required. Integrins play a crucial role in the regulation of cellular adhe...

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Detalles Bibliográficos
Autores principales: Otręba, Michał, Stojko, Jerzy, Kabała-Dzik, Agata, Rzepecka-Stojko, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073583/
https://www.ncbi.nlm.nih.gov/pubmed/35527777
http://dx.doi.org/10.3892/ol.2022.13302