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Carbon nanoparticle-protected RNA aptasensor for amplified fluorescent determination of theophylline in serum based on nuclease-aided signal amplification

A carbon nanoparticle (CNP) and Cryonase-aided method that realizes the amplified fluorescent detection of theophylline was proposed. The amplification technique exploits distinct binding affinities of CNP towards the FAM-labeled theophylline RNA aptamer (aptasensor) and aptasensor/theophylline comp...

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Detalles Bibliográficos
Autores principales: Gong, Xiaoyu, Yu, Chi, Zhang, Yichang, Sun, Yuan, Ye, Lin, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073590/
https://www.ncbi.nlm.nih.gov/pubmed/35528922
http://dx.doi.org/10.1039/c9ra06798a