Synthesis and biological evaluation of 3-nitro-4-chromanone derivatives as potential antiproliferative agents for castration-resistant prostate cancer

A series of novel 3-nitro-4-chromanones were synthesized and their in vitro cytotoxicity was evaluated on castration-resistant prostate cancer cell (CRPC) lines using the sulforhodamine B (SRB) assay. The amide derivatives showed more potent antitumor activity than their corresponding ester derivati...

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Detalles Bibliográficos
Autores principales: Chen, Huiqing, Xing, Yajing, Xie, Jia, Xie, Jiuqing, Xing, Dong, Tang, Jie, Yang, Fan, Yi, Zhengfang, Qiu, Wen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073653/
https://www.ncbi.nlm.nih.gov/pubmed/35528914
http://dx.doi.org/10.1039/c9ra06420f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073653/
https://www.ncbi.nlm.nih.gov/pubmed/35528914
http://dx.doi.org/10.1039/c9ra06420f

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