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A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects

Transfer RNAs (tRNAs) are the adaptor molecules required for reading the genetic code and producing proteins. Transfer RNA variants can lead to genome-wide mistranslation, the misincorporation of amino acids not specified by the standard genetic code into nascent proteins. While genome sequencing ha...

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Detalles Bibliográficos
Autores principales: Isaacson, Joshua R, Berg, Matthew D, Charles, Brendan, Jagiello, Jessica, Villén, Judit, Brandl, Christopher J, Moehring, Amanda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073681/
https://www.ncbi.nlm.nih.gov/pubmed/35143655
http://dx.doi.org/10.1093/g3journal/jkac035