Downregulated ALKBH5 contributes to myocardial ischemia/reperfusion injury by increasing m(6)A modification of Trio mRNA

BACKGROUND: The modification of N(6)-methyladenosine (m(6)A) is a dynamic and reversible course that might play a role in cardiovascular disease. However, the mechanisms of m(6)A modification in myocardial ischemia/reperfusion injury (MIRI) remain unclear. METHODS: A mouse model of MIRI and a cell m...

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Detalles Bibliográficos
Autores principales: Li, Jiaxin, Chen, Jieshan, Zhao, Mingyi, Li, Zhetao, Liu, Nanbo, Fang, Heng, Fang, Miaoxian, Zhu, Ping, Lei, Liming, Chen, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073777/
https://www.ncbi.nlm.nih.gov/pubmed/35530959
http://dx.doi.org/10.21037/atm-22-1289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073777/
https://www.ncbi.nlm.nih.gov/pubmed/35530959
http://dx.doi.org/10.21037/atm-22-1289

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