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Supramolecular Synthon Promiscuity in Phosphoric Acid–Dihydrogen Phosphate Ionic Cocrystals

[Image: see text] Approximately 80% of active pharmaceutical ingredients (APIs) studied as lead candidates in drug development exhibit low aqueous solubility, which typically results in such APIs being poorly absorbed and exhibiting low bioavailability. Salts of ionizable APIs and, more recently, ph...

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Detalles Bibliográficos
Autores principales: Haskins, Molly M., Lusi, Matteo, Zaworotko, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073934/
https://www.ncbi.nlm.nih.gov/pubmed/35529065
http://dx.doi.org/10.1021/acs.cgd.2c00150