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ML355 Modulates Platelet Activation and Prevents ABT-737 Induced Apoptosis in Platelets
12-lipoxigenase (12-LOX) is implicated in regulation of platelet activation processes and can be a new promising target for antiplatelet therapy. However, investigations of 12-LOX were restricted by the lack of specific and potent 12-LOX inhibitors and by controversial data concerning the role of 12...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073945/ https://www.ncbi.nlm.nih.gov/pubmed/35197320 http://dx.doi.org/10.1124/jpet.121.000973 |