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ML355 Modulates Platelet Activation and Prevents ABT-737 Induced Apoptosis in Platelets

12-lipoxigenase (12-LOX) is implicated in regulation of platelet activation processes and can be a new promising target for antiplatelet therapy. However, investigations of 12-LOX were restricted by the lack of specific and potent 12-LOX inhibitors and by controversial data concerning the role of 12...

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Detalles Bibliográficos
Autores principales:	Shpakova, Valentina, Rukoyatkina, Natalia, Al Arawe, Nada, Prilepskaya, Anna, Kharazova, Alexandra, Sharina, Iraida, Gambaryan, Stepan, Martin, Emil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Cellular and Molecular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073945/ https://www.ncbi.nlm.nih.gov/pubmed/35197320 http://dx.doi.org/10.1124/jpet.121.000973

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