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Unraveling the Impact of pH on the Crystallization of Pharmaceutical Proteins: A Case Study of Human Insulin

[Image: see text] One of the most crucial parameters in protein crystallization is pH, as it governs the protein’s electrostatic interactions. However, the fundamental role of pH on crystallization still remains unknown. Here, we systematically investigated the crystallization of human insulin (isoe...

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Detalles Bibliográficos
Autores principales: Link, Frederik J., Heng, Jerry Y. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073949/
https://www.ncbi.nlm.nih.gov/pubmed/35529069
http://dx.doi.org/10.1021/acs.cgd.1c01463