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The SARS‐CoV‐2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View

The interaction of the SARS CoV2 spike glycoprotein with two sialic acid‐containing trisaccharides (α2,3 and α2,6 sialyl N‐acetyllactosamine) has been demonstrated by NMR. The NMR‐based distinction between the signals of those sialic acids in the glycans covalently attached to the spike protein and...

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Detalles Bibliográficos
Autores principales: Unione, Luca, Moure, María J., Lenza, Maria Pia, Oyenarte, Iker, Ereño‐Orbea, June, Ardá, Ana, Jiménez‐Barbero, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074024/
https://www.ncbi.nlm.nih.gov/pubmed/35191576
http://dx.doi.org/10.1002/anie.202201432