Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans

In the human fungal pathogen Candida albicans, ARO1 encodes an essential multi-enzyme that catalyses consecutive steps in the shikimate pathway for biosynthesis of chorismate, a precursor to folate and the aromatic amino acids. We obtained the first molecular image of C. albicans Aro1 that reveals t...

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Detalles Bibliográficos
Autores principales: Stogios, Peter J, Liston, Sean D, Semper, Cameron, Quade, Bradley, Michalska, Karolina, Evdokimova, Elena, Ram, Shane, Otwinowski, Zbyszek, Borek, Dominika, Cowen, Leah E, Savchenko, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074039/
https://www.ncbi.nlm.nih.gov/pubmed/35512834
http://dx.doi.org/10.26508/lsa.202101358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074039/
https://www.ncbi.nlm.nih.gov/pubmed/35512834
http://dx.doi.org/10.26508/lsa.202101358

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