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Novel spectrofluorimetric approach for determination of ledipasvir through UV-irradiation: application to biological fluids, pharmacokinetic study and content uniformity test

A highly sensitive and specific fluorescence dependent approach was created for quantitation of a recently approved anti-HCV drug (ledipasvir). This approach relies on the innovative enhancement in fluorescence intensity of ledipasvir upon exposing the cited drug to direct UV irradiation as a photo-...

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Detalles Bibliográficos
Autores principales: Abdel-Lateef, Mohamed A., Ali, Ramadan, Omar, Mahmoud A., Derayea, Sayed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074082/
https://www.ncbi.nlm.nih.gov/pubmed/35529963
http://dx.doi.org/10.1039/c9ra07949a