Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment

Risk factors such as dysregulation of Insulin-like growth factor (IGF) signaling have been linked to Alzheimer’s disease. Here we show that Insulin-like Growth Factor Binding Protein 5 (Igfbp5), an inhibitory binding protein for insulin-like growth factor 1 (Igf-1) accumulates in hippocampal pyramid...

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Detalles Bibliográficos
Autores principales: Rauskolb, Stefanie, Andreska, Thomas, Fries, Sophie, von Collenberg, Cora Ruedt, Blum, Robert, Monoranu, Camelia-Maria, Villmann, Carmen, Sendtner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074221/
https://www.ncbi.nlm.nih.gov/pubmed/35513854
http://dx.doi.org/10.1186/s40478-022-01352-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074221/
https://www.ncbi.nlm.nih.gov/pubmed/35513854
http://dx.doi.org/10.1186/s40478-022-01352-5

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