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Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

BACKGROUND: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infecting horses but anthelmintic resistance undermines treatment approaches. The molecular mechanisms underlying drug activity and resistance remain poorly understood in this parasite since experimental i...

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Detalles Bibliográficos
Autores principales: Dube, Faruk, Hinas, Andrea, Roy, Shweta, Martin, Frida, Åbrink, Magnus, Svärd, Staffan, Tydén, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074254/
https://www.ncbi.nlm.nih.gov/pubmed/35513885
http://dx.doi.org/10.1186/s13071-022-05260-4