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Tetraspanin 7 promotes osteosarcoma cell invasion and metastasis by inducing EMT and activating the FAK-Src-Ras-ERK1/2 signaling pathway

BACKGROUND: Tetraspanins are members of the 4-transmembrane protein superfamily (TM4SF) that function by recruiting many cell surface receptors and signaling proteins into tetraspanin-enriched microdomains (TEMs) that play vital roles in the regulation of key cellular processes including adhesion, m...

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Detalles Bibliográficos
Autores principales: Shao, Shijie, Piao, Lianhua, Guo, Liwei, Wang, Jiangsong, Wang, Luhui, Wang, Jiawen, Tong, Lei, Yuan, Xiaofeng, Zhu, Junke, Fang, Sheng, Wang, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074275/
https://www.ncbi.nlm.nih.gov/pubmed/35524311
http://dx.doi.org/10.1186/s12935-022-02591-1