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ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive oxygen species (ROS)-induced excessive fibroblast-to-myofibroblast transition and extracellular matrix deposition. Macrophag...

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Detalles Bibliográficos
Autores principales: Liu, Junzhao, Wu, Zuohong, Liu, Yadong, Zhan, Zhu, Yang, Liping, Wang, Can, Jiang, Qinqin, Ran, Haitao, Li, Pan, Wang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074278/
https://www.ncbi.nlm.nih.gov/pubmed/35524280
http://dx.doi.org/10.1186/s12951-022-01435-4