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Qualitative and quantitative assessment of genotoxins using SRRz lysis reporter under the control of a newly designed SOS responsive promoter in Escherichia coli

A new bacterial genotoxicity detection strain was constructed, in which the cell lysis gene of SRRz from a lambda phage was controlled by a new designed SOS responsive element, designated as Escherichia coli BL21/pUC-PST. The biosensor responded only after 0.5 h contact with mutagens and the changes...

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Detalles Bibliográficos
Autores principales: Yuan, Pengfei, Dong, Junqing, Zhao, Weibin, Zhuo, Min, Li, Shuang, Huang, Shaobin, Li, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074414/
https://www.ncbi.nlm.nih.gov/pubmed/35528065
http://dx.doi.org/10.1039/c9ra06202e