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SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes

SOX4 belongs to the group C of the SOX transcription factor family. It is a critical mediator of tumor necrosis factor alpha (TNF)-induced transformation of fibroblast-like s-ynoviocytes (FLS) in arthritis. In this study we investigated the genome wide association between the DNA binding and transcr...

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Detalles Bibliográficos
Autores principales: Jones, Kyle, Ramirez-Perez, Sergio, Niu, Sean, Gangishetti, Umesh, Drissi, Hicham, Bhattaram, Pallavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074688/
https://www.ncbi.nlm.nih.gov/pubmed/35529852
http://dx.doi.org/10.3389/fimmu.2022.789349