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SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes
SOX4 belongs to the group C of the SOX transcription factor family. It is a critical mediator of tumor necrosis factor alpha (TNF)-induced transformation of fibroblast-like s-ynoviocytes (FLS) in arthritis. In this study we investigated the genome wide association between the DNA binding and transcr...
Autores principales: | Jones, Kyle, Ramirez-Perez, Sergio, Niu, Sean, Gangishetti, Umesh, Drissi, Hicham, Bhattaram, Pallavi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074688/ https://www.ncbi.nlm.nih.gov/pubmed/35529852 http://dx.doi.org/10.3389/fimmu.2022.789349 |
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