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The Yin and Yang of Pneumolysin During Pneumococcal Infection

Pneumolysin (PLY) is a pore-forming toxin produced by the human pathobiont Streptococcus pneumoniae, the major cause of pneumonia worldwide. PLY, a key pneumococcal virulence factor, can form transmembrane pores in host cells, disrupting plasma membrane integrity and deregulating cellular homeostasi...

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Detalles Bibliográficos
Autores principales: Pereira, Joana M., Xu, Shuying, Leong, John M., Sousa, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074694/
https://www.ncbi.nlm.nih.gov/pubmed/35529870
http://dx.doi.org/10.3389/fimmu.2022.878244