Bulky cations greatly increase the turnover of a native hammerhead ribozyme

Methods to facilitate the catalytic turnover of ribozymes are required for advancing oligonucleotide-based technologies. This study examined tetraalkylammonium ions for their ability to increase the efficiency of catalytic turnover of a native hammerhead ribozyme. Kinetic analysis showed that large...

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Detalles Bibliográficos
Autores principales: Nakano, Shu-ichi, Yamashita, Hirofumi, Tanabe, Kazuya, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074697/
https://www.ncbi.nlm.nih.gov/pubmed/35528091
http://dx.doi.org/10.1039/c9ra06797c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074697/
https://www.ncbi.nlm.nih.gov/pubmed/35528091
http://dx.doi.org/10.1039/c9ra06797c

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