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Bulky cations greatly increase the turnover of a native hammerhead ribozyme
Methods to facilitate the catalytic turnover of ribozymes are required for advancing oligonucleotide-based technologies. This study examined tetraalkylammonium ions for their ability to increase the efficiency of catalytic turnover of a native hammerhead ribozyme. Kinetic analysis showed that large...
Autores principales: | Nakano, Shu-ichi, Yamashita, Hirofumi, Tanabe, Kazuya, Sugimoto, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074697/ https://www.ncbi.nlm.nih.gov/pubmed/35528091 http://dx.doi.org/10.1039/c9ra06797c |
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