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Inversed Ratio of CD39/CD73 Expression on γδ T Cells in HIV Versus Healthy Controls Correlates With Immune Activation and Disease Progression

BACKGROUND: γδ T cells are unconventional T cells that have been demonstrated to be crucial for the pathogenesis and potentially for the cure of HIV-1 infection. The ectonucleotidase CD39 is part of the purinergic pathway that regulates immune responses by degradation of pro-inflammatory ATP in conc...

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Detalles Bibliográficos
Autores principales: Kolbe, Katharina, Wittner, Melanie, Hartjen, Philip, Hüfner, Anja-Dorothee, Degen, Olaf, Ackermann, Christin, Cords, Leon, Stellbrink, Hans-Jürgen, Haag, Friedrich, Schulze zur Wiesch, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074873/
https://www.ncbi.nlm.nih.gov/pubmed/35529864
http://dx.doi.org/10.3389/fimmu.2022.867167