Individualized multi-omic pathway deviation scores using multiple factor analysis

Malignant progression of normal tissue is typically driven by complex networks of somatic changes, including genetic mutations, copy number aberrations, epigenetic changes, and transcriptional reprogramming. To delineate aberrant multi-omic tumor features that correlate with clinical outcomes, we pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Rau, Andrea, Manansala, Regina, Flister, Michael J, Rui, Hallgeir, Jaffrézic, Florence, Laloë, Denis, Auer, Paul L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074877/
https://www.ncbi.nlm.nih.gov/pubmed/32766691
http://dx.doi.org/10.1093/biostatistics/kxaa029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074877/
https://www.ncbi.nlm.nih.gov/pubmed/32766691
http://dx.doi.org/10.1093/biostatistics/kxaa029

Ejemplares similares