Reversing the miRNA -5p/-3p stoichiometry reveals physiological roles and targets of miR-140 miRNAs

The chondrocyte-specific miR-140 miRNAs are necessary for normal endochondral bone growth in mice. miR-140 deficiency causes dwarfism and craniofacial deformity. However, the physiologically important targets of miR-140 miRNAs are still unclear. The miR-140 gene (Mir140) encodes three chondrocyte-sp...

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Detalles Bibliográficos
Autores principales: Young, Cameron, Caffrey, Melissa, Janton, Christopher, Kobayashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074898/
https://www.ncbi.nlm.nih.gov/pubmed/35332065
http://dx.doi.org/10.1261/rna.079013.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074898/
https://www.ncbi.nlm.nih.gov/pubmed/35332065
http://dx.doi.org/10.1261/rna.079013.121

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