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Plasticity and conditional essentiality of modification enzymes for domain V of Escherichia coli 23S ribosomal RNA

Escherichia coli rRNAs are post-transcriptionally modified at 36 positions but their modification enzymes are dispensable individually for growth, bringing into question their significance. However, a major growth defect was reported for deletion of the RlmE enzyme, which abolished a 2′O methylation...

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Detalles Bibliográficos
Autores principales: Liljeruhm, Josefine, Leppik, Margus, Bao, Letian, Truu, Triin, Calvo-Noriega, Maria, Freyer, Nicola S., Liiv, Aivar, Wang, Jinfan, Blanco, Rubén Crespo, Ero, Rya, Remme, Jaanus, Forster, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074899/
https://www.ncbi.nlm.nih.gov/pubmed/35260421
http://dx.doi.org/10.1261/rna.079096.121