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Switched reaction specificity in polyesterases towards amide bond hydrolysis by enzyme engineering

The recalcitrance of plastics like nylon and other polyamides contributes to environmental problems (e.g. microplastics in oceans) and restricts possibilities for recycling. The fact that hitherto discovered amidases (EC 3.5.1. and 3.5.2.) only show no, or low, activity on polyamides currently obstr...

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Detalles Bibliográficos
Autores principales: Biundo, Antonino, Subagia, Raditya, Maurer, Michael, Ribitsch, Doris, Syrén, Per-Olof, Guebitz, Georg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074940/
https://www.ncbi.nlm.nih.gov/pubmed/35540575
http://dx.doi.org/10.1039/c9ra07519d