Longitudinal Evaluation of Circulating Tumor DNA Using Sensitive Amplicon-Based Next-Generation Sequencing to Identify Resistance Mechanisms to Immune Checkpoint Inhibitors for Advanced Urothelial Carcinoma

Serial evaluation of circulating tumor DNA may allow noninvasive assessment of drivers of resistance to immune checkpoint inhibitors (ICIs) in advanced urothelial cancer (aUC). We used a novel, amplicon-based next-generation sequencing assay to identify genomic alterations (GAs) pre- and post-therap...

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Detalles Bibliográficos
Autores principales: Ravi, Praful, Ravi, Arvind, Riaz, Irbaz B, Freeman, Dory, Curran, Catherine, Mantia, Charlene, McGregor, Bradley A, Kilbridge, Kerry L, Pan, Chong-Xian, Pek, Michelle, Choudhury, Yukti, Tan, Min-Han, Sonpavde, Guru P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074964/
https://www.ncbi.nlm.nih.gov/pubmed/35294031
http://dx.doi.org/10.1093/oncolo/oyac037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074964/
https://www.ncbi.nlm.nih.gov/pubmed/35294031
http://dx.doi.org/10.1093/oncolo/oyac037

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