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A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose

BACKGROUND AND PURPOSE: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4(/)-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low dose of 6.25 mg. carvedilol. EXPERIMENTAL A...

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Detalles Bibliográficos
Autores principales: Eiamart, Wanna, Prompila, Nantaporn, Jumroen, Yaowatree, Sayankuldilok, Nonlanee, Chariyavilaskul, Pajaree, Wittayalertpanya, Supeecha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075024/
https://www.ncbi.nlm.nih.gov/pubmed/35531138
http://dx.doi.org/10.4103/1735-5362.343077