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A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose
BACKGROUND AND PURPOSE: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4(/)-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low dose of 6.25 mg. carvedilol. EXPERIMENTAL A...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075024/ https://www.ncbi.nlm.nih.gov/pubmed/35531138 http://dx.doi.org/10.4103/1735-5362.343077 |