Blockade of mIL‐6R alleviated lipopolysaccharide‐induced systemic inflammatory response syndrome by suppressing NF‐κB‐mediated Ccl2 expression and inflammasome activation

Systemic inflammatory response syndrome (SIRS) is characterized by dysregulated cytokine release, immune responses and is associated with organ dysfunction. IL‐6R blockade indicates promising therapeutic effects in cytokine release storm but still remains unknown in SIRS. To address the issue, we ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Ji‐Min, Zhang, Xue‐Qin, Zhang, Jia‐Jia, Yang, Wei‐Jie, Yang, Xiang‐Min, Bian, Huijie, Chen, Zhi‐Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075038/
https://www.ncbi.nlm.nih.gov/pubmed/35548710
http://dx.doi.org/10.1002/mco2.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075038/
https://www.ncbi.nlm.nih.gov/pubmed/35548710
http://dx.doi.org/10.1002/mco2.132

Ejemplares similares