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S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia

BACKGROUND: Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation and nitrosative stress. METHODS AND RESULTS: Here, we...

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Detalles Bibliográficos
Autores principales: Kulandavelu, Shathiyah, Dulce, Raul A., Murray, Christopher I., Bellio, Michael A., Fritsch, Julia, Kanashiro‐Takeuchi, Rosemeire, Arora, Himanshu, Paulino, Ellena, Soetkamp, Daniel, Balkan, Wayne, Van Eyk, Jenny E., Hare, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075059/
https://www.ncbi.nlm.nih.gov/pubmed/35191317
http://dx.doi.org/10.1161/JAHA.121.024008