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Ethnic differences in ApoC-III concentration and the risk of cardiovascular disease: No evidence for the cardioprotective role of rare/loss of function APOC3 variants in non-Europeans

BACKGROUND: Hypertriglyceridemia is as an independent risk factor for cardiovascular disease (CVD). Apolipoprotein C-III (ApoC-III) is known to regulate triglyceride (TG) metabolism. However, the causal association between ApoC-III and CVD development is unclear. The objectives were to examine the i...

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Detalles Bibliográficos
Autores principales: Rout, Madhusmita, Lerner, Megan, Blackett, Piers R., Peyton, Marvin D., Stavrakis, Stavros, Sidorov, Evgeny, Sanghera, Dharambir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075110/
https://www.ncbi.nlm.nih.gov/pubmed/35528316
http://dx.doi.org/10.1016/j.ahjo.2022.100128