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Metagenomic ene-reductases for the bioreduction of sterically challenging enones

Ene-reductases (ERs) of the Old Yellow Enzyme family catalyse asymmetric reduction of activated alkenes providing chiral products. They have become an important method in the synthetic chemists' toolbox offering a sustainable alternative to metal-catalysed asymmetric reduction. Development of n...

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Detalles Bibliográficos
Autores principales: Dobrijevic, Dragana, Benhamou, Laure, Aliev, Abil E., Méndez-Sánchez, Daniel, Dawson, Natalie, Baud, Damien, Tappertzhofen, Nadine, Moody, Thomas S., Orengo, Christine A., Hailes, Helen C., Ward, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075147/
https://www.ncbi.nlm.nih.gov/pubmed/35539044
http://dx.doi.org/10.1039/c9ra06088j