Hippo Pathway Effector Tead1 Induces Cardiac Fibroblast to Cardiomyocyte Reprogramming

BACKGROUND: The conversion of fibroblasts into induced cardiomyocytes may regenerate myocardial tissue from cardiac scar through in situ cell transdifferentiation. The efficiency transdifferentiation is low, especially for human cells. We explored the leveraging of Hippo pathway intermediates to enh...

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Detalles Bibliográficos
Autores principales: Singh, Vivek P., Pinnamaneni, Jaya P., Pugazenthi, Aarthi, Sanagasetti, Deepthi, Mathison, Megumi, Martin, James F., Yang, Jianchang, Rosengart, Todd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075224/
https://www.ncbi.nlm.nih.gov/pubmed/34889103
http://dx.doi.org/10.1161/JAHA.121.022659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075224/
https://www.ncbi.nlm.nih.gov/pubmed/34889103
http://dx.doi.org/10.1161/JAHA.121.022659

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