Increased Lung Uric Acid Deteriorates Pulmonary Arterial Hypertension

BACKGROUND: Recent studies have demonstrated that uric acid (UA) enhances arginase activity, resulting in decreased NO in endothelial cells. However, the role of lung UA in pulmonary arterial hypertension (PAH) remains uncertain. We hypothesized that increased lung UA level contributes to the progre...

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Detalles Bibliográficos
Autores principales: Watanabe, Takanori, Ishikawa, Mariko, Abe, Kohtaro, Ishikawa, Tomohito, Imakiire, Satomi, Masaki, Kohei, Hosokawa, Kazuya, Fukuuchi, Tomoko, Kaneko, Kiyoko, Ohtsubo, Toshio, Hirano, Mayumi, Hirano, Katsuya, Tsutsui, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075373/
https://www.ncbi.nlm.nih.gov/pubmed/34845934
http://dx.doi.org/10.1161/JAHA.121.022712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075373/
https://www.ncbi.nlm.nih.gov/pubmed/34845934
http://dx.doi.org/10.1161/JAHA.121.022712

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