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Brain Kynurenine Pathway and Functional Outcome of Rats Resuscitated From Cardiac Arrest

BACKGROUND: Brain injury and neurological deficit are consequences of cardiac arrest (CA), leading to high morbidity and mortality. Peripheral activation of the kynurenine pathway (KP), the main catabolic route of tryptophan metabolized at first into kynurenine, predicts poor neurological outcome in...

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Detalles Bibliográficos
Autores principales: Lucchetti, Jacopo, Fumagalli, Francesca, Olivari, Davide, Affatato, Roberta, Fracasso, Claudia, De Giorgio, Daria, Perego, Carlo, Motta, Francesca, Passoni, Alice, Staszewsky, Lidia, Novelli, Deborah, Magliocca, Aurora, Garattini, Silvio, Latini, Roberto, Ristagno, Giuseppe, Gobbi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075408/
https://www.ncbi.nlm.nih.gov/pubmed/34816736
http://dx.doi.org/10.1161/JAHA.121.021071