Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

BACKGROUND: Platelet‐derived growth factor is a major regulator of the vascular remodeling associated with pulmonary arterial hypertension. We previously showed that protein widely 1 (PW1(+)) vascular progenitor cells participate in early vessel neomuscularization during experimental pulmonary hyper...

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Detalles Bibliográficos
Autores principales: Solinc, Julien, Raimbault‐Machado, Jessica, Dierick, France, El Bernoussi, Lamiaa, Tu, Ly, Thuillet, Raphaël, Mougenot, Nathalie, Hoareau‐Coudert, Bénédicte, Monceau, Virginie, Pavoine, Catherine, Atassi, Fabrice, Sassoon, David, Marazzi, Giovanna, Harvey, Richard P., Schofield, Peter, Christ, Daniel, Humbert, Marc, Guignabert, Christophe, Soubrier, Florent, Nadaud, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075467/
https://www.ncbi.nlm.nih.gov/pubmed/35348002
http://dx.doi.org/10.1161/JAHA.121.023021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075467/
https://www.ncbi.nlm.nih.gov/pubmed/35348002
http://dx.doi.org/10.1161/JAHA.121.023021

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