Tissue‐Specific Roles for the Slit–Robo Pathway During Heart, Caval Vein, and Diaphragm Development

BACKGROUND: Binding of Slit ligands to their Robo receptors regulates signaling pathways that are important for heart development. Genetic variants in ROBO1and ROBO4 have been linked to congenital heart defects in humans. These defects are recapitulated in mouse models with ubiquitous deletions of t...

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Detalles Bibliográficos
Autores principales: Zhao, Juanjuan, Bruche, Susann, Potts, Helen G., Davies, Benjamin, Mommersteeg, Mathilda T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075489/
https://www.ncbi.nlm.nih.gov/pubmed/35343246
http://dx.doi.org/10.1161/JAHA.121.023348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075489/
https://www.ncbi.nlm.nih.gov/pubmed/35343246
http://dx.doi.org/10.1161/JAHA.121.023348

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